A Catalyst‐Free Minisci‐Type Reaction: the C–H Alkylation of Quinoxalinones with Sodium Alkylsulfinates and Phenyliodine(III) Dicarboxylates | Zendy

Wang Liping | Zendy; Zhao Jiquan | Zendy; Sun Yuting | Zendy; Zhang HongYu | Zendy; Zhang Yuecheng | Zendy

Premium

A Catalyst‐Free Minisci‐Type Reaction: the C–H Alkylation of Quinoxalinones with Sodium Alkylsulfinates and Phenyliodine(III) Dicarboxylates

Author(s) -

Wang Liping,

Zhao Jiquan,

Sun Yuting,

Zhang HongYu,

Zhang Yuecheng

Publication year - 2019

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201901266

Subject(s) - chemistry , alkylation , catalysis , sodium , medicinal chemistry , organic chemistry , combinatorial chemistry

A direct C–H alkylation of quinoxalinones at the C‐3 position with sodium alkylsulfinates and phenyliodine(III) dicarboxylates has been developed under catalyst‐free conditions. A series of 3‐alkylquinoxalinones were afforded in moderate to excellent yields in this protocol, which offers a practical and efficient access to biologically interesting 3‐alkylquinoxalin‐2(1 H )‐one derivatives.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research