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Cover Feature: Isomerization and Dimerization of Indocyanine Green and a Related Heptamethine Dye (Eur. J. Org. Chem. 30/2019)
Author(s) -
Rüttger Franziska,
Mindt Sonani,
Golz Christopher,
Alcarazo Manuel,
John Michael
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201901145
Subject(s) - chemistry , indocyanine green , isomerization , photochemistry , photoisomerization , dimer , absorption (acoustics) , organic chemistry , catalysis , pathology , optics , medicine , physics
The Cover Feature shows the dimer of Indocyanine Green (ICG), a dye that is currently widely employed in the diagnostics of hepatitic function, angiography, and tumor imaging and surgery. The highly specific formation of the central C–C bond between the two ICG heptamethine chains requires both light (ICG absorption maximum ≈ 800 nm) and molecular oxygen. Furthermore, ICG undergoes trans ‐ cis photoisomerization of its heptamethine chain, and these isomers are also detected by low‐temperature NMR spectroscopy. More information can be found in the Communication by M. John et al.