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Intermolecular Aminoallylation of Alkenes Using Allyl‐Oxyphthalimide Derivatives: A Case Study in Radical Polarity Effects
Author(s) -
Lardy Samuel W.,
Schmidt Valerie A.
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201901071
Subject(s) - chemistry , alkene , polarity (international relations) , intermolecular force , reactivity (psychology) , radical cyclization , radical , photochemistry , computational chemistry , medicinal chemistry , organic chemistry , molecule , catalysis , medicine , biochemistry , alternative medicine , pathology , cell
A case study on the polarity effects of radical mediated intermolecular alkene aminoallylation is presented herein. This radical group transfer method pairs vinyl ethers with electronically deficient allyl‐oxyphthalimide derivatives to give difunctionalized products while illustrating the guiding effects of polarity on this radical reactivity.