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Organocatalytic Asymmetric Synthesis of Tetrahydrofuran and 1,2‐Dihydrobenzofuran Scaffolds
Author(s) -
Chavan Lahu N.,
Mainkar Prathama S.,
Chandrasekhar S.
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201901067
Subject(s) - chemistry , tetrahydrofuran , dibenzofuran , organocatalysis , enantioselective synthesis , catalysis , combinatorial chemistry , organic chemistry , solvent
Asymmetric synthesis of substituted tetrahydrofurans and dibenzofurans is emerging as a challenging field. Use of organocatalysis has been explored extensively to achieve the asymmetry involves mild conditions and control over enantio‐ and diastereoselectivity for the synthesis of substituted THF and DHB. A review of various conditions and catalysts developed so far towards the synthesis of substituted tetrahydrofuran and dibenzofuran are presented here.