The Cascade Methylation/Cyclization of  ortho ‐Cyanoarylacrylamides with Dicumyl Peroxide | Zendy

Yang Tao | Zendy; Xia WenJin | Zendy; Zhou Bin | Zendy; Xin Yangchun | Zendy; Shen Yuehai | Zendy; Li YaMin | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

The Cascade Methylation/Cyclization of ortho ‐Cyanoarylacrylamides with Dicumyl Peroxide

Author(s) -

Yang Tao,

Xia WenJin,

Zhou Bin,

Xin Yangchun,

Shen Yuehai,

Li YaMin

Publication year - 2019

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201900918

Subject(s) - chemistry , methylation , reagent , cascade , quinoline , peroxide , combinatorial chemistry , hydrogen peroxide , substrate (aquarium) , transformation (genetics) , scope (computer science) , organic chemistry , chromatography , biochemistry , oceanography , computer science , gene , programming language , geology

A radical cascade methylation/cyclization of ortho ‐cyanoarylacrylamides was developed by utilizing dicumyl peroxide as a methylation reagent. This transformation provides a simple and straightforward approach to methylated quinoline‐2,4(1 H ,3 H )‐diones, and exhibits a wide substrate scope. Furthermore, this reaction could be readily scaled up. A possible mechanism is also proposed.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research