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Highly Water‐Soluble Amphiphilic Cyclodextrins Bearing Branched and Cyclic Oleic Grafts
Author(s) -
Cocq Aurélien,
Rousseau Cyril,
Bricout Hervé,
Oliva Estefanía,
Bonnet Véronique,
DjedaïniPilard Florence,
Monflier Eric,
Tilloy Sébastien
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201900789
Subject(s) - succinic anhydride , oleic acid , chemistry , amphiphile , grafting , maleic anhydride , cyclodextrin , organic chemistry , acylation , succinic acid , polymer chemistry , catalysis , copolymer , biochemistry , polymer
Amphiphilic β‐cyclodextrins bearing various amounts of branched and cyclic oleic grafts are synthetized. The first step of this synthesis is the alkenylation of maleic anhydride by oleic acid derivatives, in the presence of a rhodium catalyst, to produce oleic succinic anhydrides with different ratios of cyclic to branched groups. The second step is the grafting of the oleic succinic anhydrides mixtures on β‐cyclodextrin. The obtained cyclodextrins are highly water‐soluble and surface active.