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Visible‐Light‐Induced Ring‐Opening of Hydrogenolysis Spirocyclopropyl Oxindoles Through Photoredox Catalysis
Author(s) -
Liu ZhiPing,
Li JinLian,
Cheng XiuLiang,
Cui JianGuo,
Huang YanMing,
Gan ChunFang,
Su Wei,
Xiao JunAn
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201900696
Subject(s) - hydrogenolysis , chemistry , oxindole , photoredox catalysis , ring (chemistry) , catalysis , combinatorial chemistry , photochemistry , organic chemistry , photocatalysis
An efficient photoredox‐catalyzed ring‐opening hydrogenolysis of spirocyclopropyl oxindoles by using diisopropylethylamine as reducing agent has been developed. Varieties of 3‐substituted oxindole derivatives were achieved in moderate to good yields under mild reaction conditions. Furthermore, the synthetic utility is demonstrated by further transformations of the synthesized products.