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An Expeditious and Environmentally‐Benign Approach to 2‐Aryl/Heteroaryl Selenopyridines via Ruthenium Catalyzed [2+2+2] Cycloadditions
Author(s) -
Kalaramna Pratibha,
Bhatt Divya,
Sharma Himanshu,
Goswami Avijit
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201900664
Subject(s) - chemistry , aryl , ruthenium , catalysis , cycloaddition , combinatorial chemistry , atom economy , organic chemistry , alkyl
A highly efficient protocol for the synthesis of 2‐aryl/ hetero aryl selenopyridines has been developed via a ruthenium(II)‐catalyzed cycloaddition reaction of 1,6‐diynes with aryl/heteroaryl selenocyanates with good to excellent yields. It was found that various diynes and selenocyanates expediently underwent the reaction under open‐flask conditions. This atom‐economical catalytic strategy offers a mild and practical approach to access a variety of such cycloadducts with excellent regioselectivities.