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Smooth Metal‐Free Photoinduced Preparation of Valuable 8‐Arylxanthines
Author(s) -
Abdulla Havall Othman,
Amin Ahmed A.,
Raviola Carlotta,
Opatz Till,
Protti Stefano,
Fagi Maurizio
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201900638
Subject(s) - chemistry , xanthine , theophylline , aqueous solution , metal , combinatorial chemistry , photochemistry , organic chemistry , medicine , enzyme , endocrinology
A set of 8‐arylxanthines was prepared under metal‐free conditions and in aqueous solvents from arylazo sulfones and caffeine or theophylline. Notably, the process took place by simply exposing the reaction vessel to visible or solar light, and unreacted xanthine could be easily recovered during the purification step.