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Cover Feature: Evaluation of the Steric Bulk of Substituents Utilizing the Shuttling Behavior of [2]Rotaxanes with N ‐Arylpyrrole Moieties (Eur. J. Org. Chem. 21/2019)
Author(s) -
Yamashita Yoshiaki,
Saito Yuuki,
Kikkawa Shoko,
Mutoh Yuichiro,
Hosoya Shoichi,
Azumaya Isao,
Saito Shinichi
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201900595
Subject(s) - substituent , chemistry , moiety , rotaxane , steric effects , ring (chemistry) , pyrrole , ring size , molecular machine , stereochemistry , crystallography , nanotechnology , organic chemistry , supramolecular chemistry , materials science , crystal structure
The Cover Feature shows a new method for the determination of substituent size by “jumping through flaming hoop” method. The size of a brave tiger can be measured by the size of the hoop: a large tiger cannot pass through the hoop, though a small tiger jumps through the hoop. At the molecular level, the substituent size could be determined by using a macrocyclic ring as the “flaming hoop”. The size of a substituent was quantitatively measured by observing the activation energy for the shuttling process of a [2]rotaxane with pyrrole moiety incorporating a substituent. More information can be found in the Full Paper by I. Azumaya, S. Saito et al.

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