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Front Cover: Incremental Introduction of Organocatalytic Activity into Conformationally Engineered Porphyrins (Eur. J. Org. Chem. 14/2019)
Author(s) -
Kielmann Marc,
Grover Nitika,
Kalisch Werner W.,
Senge Mathias O.
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201900454
Subject(s) - chemistry , bifunctional , porphyrin , front cover , cover (algebra) , organocatalysis , core (optical fiber) , catalysis , stereochemistry , combinatorial chemistry , enantioselective synthesis , organic chemistry , computer science , mechanical engineering , telecommunications , engineering
The Front Cover shows porphyrins training and flexing their aromatic bodies in the gym to get themselves into shape for new applications. A thorough molecular exercise regime boosts muscle mass here illustrated by bulkier residues resulting in nonplanar macrocycles. These molecular gymnastics, coached by molecular engineering, allowed us to modify the conformation and catalytic properties of highly substituted, nonplanar porphyrins. Putting them through the paces of a conformational control fitness program, we were able to gradually access their 'hidden' bifunctional core and to create metal‐free porphyrin organocatalysts for Michael additions. Cover design by Ella Marushchenko. More information can be found in the Full Paper by M. O. Senge et al.