Minisci‐Type C–H Cyanoalkylation of Heteroarenes Through N–O/C–C Bonds Cleavage | Zendy

Jian Yong | Zendy; Chen Ming | Zendy; Yang Chao | Zendy; Xia Wujiong | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Minisci‐Type C–H Cyanoalkylation of Heteroarenes Through N–O/C–C Bonds Cleavage

Author(s) -

Jian Yong,

Chen Ming,

Yang Chao,

Xia Wujiong

Publication year - 2020

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201900406

Subject(s) - chemistry , cleavage (geology) , radical , bond cleavage , substrate (aquarium) , stereochemistry , combinatorial chemistry , medicinal chemistry , catalysis , organic chemistry , oceanography , geotechnical engineering , fracture (geology) , engineering , geology

A visible‐light‐induced C–H cyanoalkylation of heteroarenes was described, in which cycloketone oximes were readily transformed into carbon‐centered radicals with a terminal cyano‐group via N–O/C–C bonds cleavage in one phtochemical step. This reaction protocol displayed a broad substrate scope of heterocycle compounds, and it provided a promising strategy for the installation of cyanoalkyl groups onto heteroarenes.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research