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Metal‐Free and Visible‐Light‐Promoted C‐3 Thiocyanation of 2‐Arylquinolin‐4‐ones
Author(s) -
Chauhan Parul,
Kumar Sharvan,
Jain Nidhi
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201900349
Subject(s) - chemistry , eosin y , regioselectivity , aryl , visible spectrum , green light , metal , photochemistry , reaction conditions , eosin , combinatorial chemistry , organic chemistry , catalysis , photocatalysis , blue light , staining , alkyl , physics , optoelectronics , medicine , pathology , optics
A C‐3 thiocyanation of 2‐aryl‐quinolin‐4‐ones in the presence of eosin‐Y and visible light has been developed. The methodology allows easy access to a variety of 2‐aryl‐3‐thiocyano‐quinolin‐4‐ones in moderate to high yields. Regioselective para ‐thiocyanation of anilines has also been achieved under these conditions. The reaction is operationally simple, metal‐free, requires air as the oxidant, and proceeds smoothly at room temperature.