Premium
The Impact of Recent Developments in Technologies which Enable the Increased Use of Biocatalysts
Author(s) -
Foley Aoife M.,
Maguire Anita R.
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201900208
Subject(s) - biocatalysis , chemistry , reusability , enantioselective synthesis , scope (computer science) , biochemical engineering , nanotechnology , substrate (aquarium) , flow chemistry , combinatorial chemistry , green chemistry , organic chemistry , catalysis , ionic liquid , computer science , engineering , ecology , materials science , programming language , biology , software
While biocatalytic transformations are very powerful in enantioselective synthesis, frequently occurring under mild conditions, and proceed with extraordinary selectivity, there are practical challenges associated with the use of biocatalysis, such as limited substrate scope, stability, and reusability. Recent technological developments, for example immobilization, continuous flow, and molecular biology, all contribute towards enhancing the use of enzymes in synthesis.