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Ligand‐Free Palladium(II)‐Catalyzed ortho ‐C–H Chalcogenations of N ‐Arylsulfonamide via Weak Coordination
Author(s) -
Gu Linghui,
Fang Xinyue,
Weng Zhengyun,
Song Yupin,
Ma Wenbo
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201900050
Subject(s) - chemistry , palladium , ligand (biochemistry) , catalysis , selectivity , substrate (aquarium) , stereochemistry , combinatorial chemistry , medicinal chemistry , organic chemistry , receptor , biochemistry , oceanography , geology
The first palladium(II)‐catalyzed direct ortho ‐C(sp 2 )–H chalcogenations of N ‐arylsulfonamide via weak coordination have been achieved, affording the corresponding mono‐chalocgenated products in good to excellent yields. This strategy features ligand/additive‐free conditions, broad substrate scope with excellent functional group tolerance and a high position selectivity.