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Construction of Di(hetero)arylmethanes Through Pd‐Catalyzed Direct Dehydroxylative Cross‐Coupling of Benzylic Alcohols and Aryl Boronic Acids Mediated by Sulfuryl Fluoride (SO 2 F 2 )
Author(s) -
Zhao Chuang,
Zha GaoFeng,
Fang WanYin,
Rakesh K. P.,
Qin HuaLi
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801888
Subject(s) - chemistry , catalysis , aryl , fluoride , organic chemistry , palladium , combinatorial chemistry , coupling (piping) , medicinal chemistry , inorganic chemistry , mechanical engineering , alkyl , engineering
A practical Pd‐catalyzed direct dehydroxylative coupling of (hetero)benzylic alcohols with (hetero)arylboronic acids for the constructions of di(hetero)arylmethane derivatives under SO 2 F 2 was described. This new method provided a strategically distinct approach to di(hetero)arylmethane derivatives from readily available and abundant benzylic alcohols under mild condition.