Premium
Electrochemical Cross‐Dehydrogenative Coupling of N ‐Aryl‐tetrahydroisoquinolines with Phosphites and Indole
Author(s) -
Xie Wenxia,
Liu Nian,
Gong Bowen,
Ning Shulin,
Che Xin,
Cui Lili,
Xiang Jinbao
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801883
Subject(s) - chemistry , reagent , indole test , aryl , electrochemistry , combinatorial chemistry , coupling reaction , coupling (piping) , organic chemistry , medicinal chemistry , catalysis , alkyl , electrode , mechanical engineering , engineering
A metal‐ and reagent‐free, electrochemical cross‐dehydrogenative coupling reaction of N ‐aryl‐tetrahydroisoquinolines with phosphites and indole is developed. This method provides an environmentally benign and simple approach for the construction of C–P and C–C bonds in moderate to high yields with wide tolerance of functional groups.