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Cover Feature: Hydrogen‐Bonding Interactions in the Ley–Griffith Oxidation: Practical Considerations for the Synthetic Chemist (Eur. J. Org. Chem. 2‐3/2019)
Author(s) -
Moore Peter W.,
Zerk Timothy J.,
Burns Jed M.,
Bernhardt Paul V.,
Williams Craig M.
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801822
Subject(s) - chemistry , catalysis , cover (algebra) , hydrogen bond , combinatorial chemistry , molecule , polymer science , organic chemistry , engineering , mechanical engineering
The Cover Feature shows the catalytic cycle of the Ley–Griffith oxidation, which like the site of the upcoming Heron8 conference on reactive intermediates and unusual molecules being held at Australia's iconic Uluru, works best under dry conditions. Extensive reaction monitoring has demonstrated that removal of product water by molecular sieves prevents sequestration of the co‐oxidant N ‐methylmorpholine oxide (NMO) and decomposition of the tetrapro‐pylammonium perruthenate (TPAP) catalyst, leading to practical recommendations for synthetic chemists. Cover design by Kylie Agnew‐Francis. More information can be found in the Communication by P. V. Bernhardt, C. M. Williams et al.