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Palladium(II)/Copper(II)‐Catalyzed C–H Sulfidation or Selenation of Arenes Leading to Unsymmetrical Sulfides and Selenides
Author(s) -
Nishino Kota,
Tsukahara Shouya,
Ogiwara Yohei,
Sakai Norio
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801765
Subject(s) - sulfidation , chemistry , palladium , aryl , catalysis , copper , alkyl , medicinal chemistry , organic chemistry , combinatorial chemistry , polymer chemistry
A novel palladium(II)/copper(II)‐catalyzed sulfidation of the C–H bond in electron‐rich arenes and in pentafluorobenzene with disulfides was developed. This catalytic system can be used to efficiently produce various types of either unsymmetrical aryl sulfides or alkyl aryl sulfides. The present protocol could also be applied to the direct preparation of unsymmetrical aryl selenides via C–H selenation.