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Front Cover: Why Cyclopropanation is not Involved in Photoinduced α‐Alkylation of Ketones with Diazo Compounds (Eur. J. Org. Chem. 47/2018)
Author(s) -
RybickaJasińska Katarzyna,
Orłowska Katarzyna,
Karczewski Maksymilian,
Zawada Katarzyna,
Gryko Dorota
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801429
Subject(s) - cyclopropanation , diazo , chemistry , alkylation , protonation , enamine , front cover , porphyrin , photochemistry , catalysis , medicinal chemistry , cover (algebra) , organic chemistry , ion , mechanical engineering , engineering
The Front Cover shows porphyrin, a compound vital to our life that acts as a photoredox catalyst for the direct alkylation of carbonyl compounds with diazo esters. Based on experimental and theoretical studies, a plausible mechanism involving the generation of an enamine radical cation that subsequently reacts with protonated diazo compounds thus excluding the controversial cyclopropanation‐ring opening pathway is proposed. More information can be found in the Full Paper by K. Zawada, D. Gryko et al.