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Front Cover: A Straightforward Sequential Approach for the Enantioselective Synthesis of Optically Active α‐Arylmethanol‐1,2,3‐Triazoles (Eur. J. Org. Chem. 40/2018)
Author(s) -
Andrade Floyd C. D.,
Pugnal Lucas V. B. L.,
Betim Hugo L. I.,
Vani Jéssica F.,
ZukermanSchpector Julio,
Schwab Ricardo S.
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801419
Subject(s) - enantioselective synthesis , chemistry , heteroatom , front cover , moiety , combinatorial chemistry , cover (algebra) , alkynylation , optically active , triazole , stereochemistry , organic chemistry , catalysis , ring (chemistry) , mechanical engineering , engineering
The Front Cover shows a chiral arylmethanols bearing the 1,2,3‐triazole moiety, with a variety of di(hetero)arylmethanols, which do not contain any N ‐heteroatom. Such molecules can be obtained by using a straightforward sequential approach based on the enantioselective alkynylation of aldehydes followed by a one‐pot two‐step desilylation/CuAAC, providing the products with excellent yields and high levels of enantioselectivity. More information can be found in the Full Paper by R. S. Schwab et al.