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Visible‐Light‐Mediated α‐Oxygenation of 3‐( N , N ‐Dimethylaminomethyl)‐Indoles to Aldehydes
Author(s) -
Stanek Filip,
Pawłowski Robert,
Mlynarski Jacek,
Stodulski Maciej
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801335
Subject(s) - chemistry , oxygenation , scope (computer science) , mechanism (biology) , stereochemistry , combinatorial chemistry , philosophy , epistemology , ecology , computer science , biology , programming language
The visible‐light‐mediated oxygenation of 3‐ N , N ‐(dimethylaminomethyl)‐indoles bearing various substituents afforded a series of 3‐carbaindole derivatives. Herein we describe the reaction scope, a plausible mechanism and a practical application of this transformation in the formal synthesis of (–)‐vincorine is described as well.