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Cover Feature: Recent Developments and Synthetic Applications of Nucleophilic Zirconocene Complexes from Schwartz's Reagent (Eur. J. Org. Chem. 35/2018)
Author(s) -
Pinheiro Danielle L. J.,
de Castro Pedro P.,
Amarante Giovanni W.
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801325
Subject(s) - chemistry , nucleophile , chemoselectivity , reagent , tsuji–trost reaction , cover (algebra) , halogenation , feature (linguistics) , alkylation , combinatorial chemistry , conjugate , allylic rearrangement , organic chemistry , catalysis , mechanical engineering , mathematical analysis , linguistics , philosophy , mathematics , engineering
The Cover Feature shows the preparation of nucleophilic zirconocene complexes using Schwartz's reagent and unsaturated substrates. These species are versatile building blocks which can be further employed in various transformations, such as asymmetric allylic alkylation, asymmetric conjugate addition and halogenation, forming new C–C, C–N and C–X bonds. Furthermore, recent advances on organozirconocene chemistry allows the elegant access to elaborated compounds with high regio‐ and chemoselectivity and efficient stereocontrol. More information can be found in the Microreview by G. W. Amarante et al.