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DBU‐Mediated Efficient Synthesis of Diaryl Ethynes and Enynes from 1,1‐Dibromoalkenes at Room Temperature
Author(s) -
Thummala Yadagiri,
Morri Ashok K.,
Karunakar Galla V.,
Doddi Venkata Ramana
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801143
Subject(s) - chemistry , catalysis , combinatorial chemistry , aryl , ligand (biochemistry) , medicinal chemistry , organic chemistry , biochemistry , alkyl , receptor
The reaction of 1,1‐dibromoalkenes and aryl iodides in the presence of DBU and a Pd II /Cu I catalytic system afforded diaryl alkynes and enynes at ambient temperature. Control experiments demonstrated the essential ligand role of DBU in this transformation. The unusual stability of the key catalyst, Pd 0 (DBU) 2 , allowed it to be characterized by HRMS analysis.