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Efficient Oxidation of Benzylic and Aliphatic Alcohols Using a Bioinspired Cross‐Bridged Cyclam Manganese Complex with H 2 O 2
Author(s) -
Zhang Zhan,
Khrouz Lhoussain,
Yin Guochuan,
Andrioletti Bruno
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801140
Subject(s) - cyclam , chemistry , manganese , selectivity , acetonitrile , alcohol oxidation , thioanisole , organic chemistry , lignin , medicinal chemistry , catalysis , metal
The cross‐bridged cyclam manganese complex Mn(Me 2 EBC)Cl 2 efficiently catalyzes the oxidation of benzylic and aliphatic alcohols at pH 3 in a mixture of acetonitrile and water at room temperature. The environmentally benign and high oxygen content oxidant H 2 O 2 was adopted. Conversions of the alcohols to the corresponding carbonyl compounds reached 98 % with good to excellent selectivity. In addition, several lignin model compounds were also catalytically oxidized under these conditions, with excellent conversion (up to 96 %) and selectivity (up to 99 %).