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Palladium‐Catalyzed Carbonylative Coupling Reactions of N , N ‐Bis(methanesulfonyl)amides through C–N Bond Cleavage
Author(s) -
Lim Minkyung,
Kim Hyeji,
Ban Jaeyoung,
Son Junghan,
Lee Jae Kyun,
Min SunJoon,
Lee Sang Uck,
Rhee Hakjune
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801124
Subject(s) - chemistry , palladium , cleavage (geology) , catalysis , aryl , bond cleavage , carbonylation , amide , medicinal chemistry , coupling reaction , substrate (aquarium) , organic chemistry , carbon monoxide , alkyl , oceanography , geotechnical engineering , fracture (geology) , engineering , geology
Palladium‐catalyzed carbonylative coupling reactions of various N , N ‐bis(methanesulfonyl)amides with arylboronic acids through C–N bond cleavage were carried out. The reactions proceeded under mild conditions in a short period of time without any additives to afford a wide range of unsymmetrical aryl ketones in excellent yields. This is the first example of a carbonylative coupling reaction using N , N ‐bis(methanesulfonyl)amide as a coupling substrate.