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Benzisothiazol‐3‐ones through a Metal‐Free Intramolecular N–S Bond Formation
Author(s) -
Yang Ke,
Zhang Hao,
Niu Ben,
Tang Tiandi,
Ge Haibo
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201801090
Subject(s) - selectfluor , chemistry , intramolecular force , combinatorial chemistry , functional group , compatibility (geochemistry) , organic chemistry , stereochemistry , chemical engineering , catalysis , engineering , polymer
The highly efficient synthesis of benzoisothiazol‐3‐ones from thiobenzamides has been described with good functional group compatibility and excellent yields. This work represents the first example of selectfluor‐promoted N–S bond formation processes. This method provides a facile approach to access various important bioactive benzoisothiazol‐3‐ones.