Insights into the Structure and Function of a Chiral Conjugate‐Base‐Stabilized Brønsted Acid Catalyst | Zendy

Odagi Minami | Zendy; Araki Hiroshi | Zendy; Min Chang | Zendy; Yamamoto Eri | Zendy; Emge Thomas J. | Zendy; Yamanaka Masahiro | Zendy; Seidel Daniel | Zendy

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Insights into the Structure and Function of a Chiral Conjugate‐Base‐Stabilized Brønsted Acid Catalyst

Author(s) -

Odagi Minami,

Araki Hiroshi,

Min Chang,

Yamamoto Eri,

Emge Thomas J.,

Yamanaka Masahiro,

Seidel Daniel

Publication year - 2019

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201801024

Subject(s) - chemistry , brønsted–lowry acid–base theory , conjugate , catalysis , base (topology) , function (biology) , organic chemistry , stereochemistry , combinatorial chemistry , mathematical analysis , mathematics , evolutionary biology , biology

A combined experimental and computational study reveals key catalyst‐substrate interactions and the main factors controlling stereoselectivity in an asymmetric Pictet–Spengler reaction facilitated by a carboxylic‐acid‐thiourea catalyst.

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