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Mechanisms in Frustrated Lewis Pair‐Catalyzed Reactions
Author(s) -
Paradies Jan
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201800944
Subject(s) - frustrated lewis pair , chemistry , reactivity (psychology) , borane , catalysis , phosphine , boranes , amine gas treating , metathesis , carbon fibers , reaction mechanism , lewis acids and bases , computational chemistry , organic chemistry , polymerization , medicine , polymer , alternative medicine , materials science , pathology , composite number , boron , composite material
This review summarizes the principle reaction mechanisms of frustrated Lewis pairs (FLP) in hydrogenations and carbon–nitrogen and carbon–carbon bond forming reactions. The fundamental mechanism of hydrogen activation by FLPs is reviewed and the influence of the FLP's nature on hydrogenation reactions is discussed, leading to a structure‐reactivity relationship in phosphine/borane or amine/borane derived FLPs. This reactivity concept is validated for a series of FLP‐catalyzed reactions. Furthermore, alternative reaction mechanisms e.g. protodeborylations or σ‐bond metathesis are discussed.