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Silver‐Catalyzed Chemo‐ and Regioselective Nitration of Anilides
Author(s) -
Kianmehr Ebrahim,
Nasab Sepideh Bahrami
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201800779
Subject(s) - nitration , regioselectivity , chemistry , catalysis , sodium nitrite , combinatorial chemistry , functional group , surface modification , organic chemistry , polymer
A new and efficient Ag‐catalyzed method for the nitration of anilides by using sodium nitrite as a cheap and available NO 2 source has been developed. This C–H functionalization reaction is ortho ‐selective, achieves moderate to high yields and shows excellent functional group tolerance. Furthermore, it provides a novel approach to ortho ‐nitrated anilides, which are very tricky to access with traditional methods.