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Front Cover: Regioselective 1,3‐Dipolar Cycloadditions of Diazoalkanes with Heteroatom‐Substituted Alkynes: Theory and Experiment (Eur. J. Org. Chem. 20‐21/2018)
Author(s) -
Breugst Martin,
Huisgen Rolf,
Reissig HansUlrich
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201800739
Subject(s) - regioselectivity , chemistry , diazomethane , heteroatom , front cover , ethyl diazoacetate , cycloaddition , computational chemistry , cover (algebra) , organic chemistry , cyclopropanation , catalysis , ring (chemistry) , mechanical engineering , engineering
The Front Cover shows the regioselective 1,3‐dipolar cycloadditions of different substituted alkynes and diazomethane. 130 years after Buchner's first report on the cycloadditions of ethyl diazoacetate and 60 years after the first investigations of diazoalkane cycloadditions to strained systems, a joint experimental and computational analysis now provides an explanation for the different regioselectivities observed in these reactions. More information can be found in the Full Paper by M. Breugst, R. Huisgen, and H.‐U. Reissig . Also see the ChemViews Magazine interview with the authors .