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Front Cover: High Pressure Elicits Unexpected Transformations of Plain Nitroaromatics with 4‐(Cyclohex‐1‐en‐1‐yl)morpholine (Eur. J. Org. Chem. 18/2018)
Author(s) -
Diab Sonia,
NoëlDuchesneau Ludovik,
Sanselme Morgane,
Kondo Yoshinori,
De Paolis Michael,
Chataigner Isabelle
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201800644
Subject(s) - morpholine , chemistry , enamine , cover (algebra) , front cover , catalysis , transformation (genetics) , simple (philosophy) , combinatorial chemistry , organic chemistry , stereochemistry , mechanical engineering , biochemistry , philosophy , epistemology , engineering , gene
The Front Cover shows that high pressures activate the transformation of simple aromatic substrates into complex structures efficiently through an unexpected reaction sequence in the absence of any chemical catalyst. This technique allows simple nitroarenes to react with a readily available enamine, 4‐(cyclohex‐1‐en‐1‐yl) morpholine, in a one‐pot transformation to generate highly substituted compounds never described before, under green conditions requiring a low‐energy input. More information can be found in the Communication by I. Chataigner et al.