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Front Cover: Catalytic C‐Alkylation of Pyrroles with Primary Alcohols: Hans Fischer's Alkali and a New Method with Iridium P,N,P‐Pincer Complexes (Eur. J. Org. Chem. 14/2018)
Author(s) -
Koller Sebastian,
Blazejak Max,
Hintermann Lukas
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201800514
Subject(s) - chemistry , pincer movement , iridium , alkylation , pyrrole , front cover , catalysis , organic chemistry , iminium , alkali metal , medicinal chemistry , cover (algebra) , mechanical engineering , engineering
The Front Cover shows a collage with a stylized portrait of the 1930 chemistry Nobel prize winner, Hans Fischer. It includes motives from Fischer's lifework on the structure elucidation and synthesis of pyrrole derivatives, including porphyrins and complex plant pigments, such as chlorophyll. In 1912, Hans Fischer reported an intriguing alkylation of pyrroles with alcohols by what now appears to be a “borrowing‐hydrogen” reaction involving hydrogen autotransfer (HAT). The use of iridium pincer complexes as catalysts in this chemistry now results in much milder reaction conditions. More information can be found in the Full Paper by L. Hintermann et al.