z-logo
Premium
Visible‐Light‐Mediated Eosin Y Photoredox‐Catalyzed Vicinal Thioamination of Alkynes: Radical Cascade Annulation Strategy for 2‐Substituted‐3‐sulfenylindoles
Author(s) -
Tambe Shrikant D.,
Rohokale Rajendra S.,
Kshirsagar Umesh A.
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201800287
Subject(s) - eosin y , chemistry , vicinal , annulation , photoredox catalysis , visible spectrum , photochemistry , catalysis , substrate (aquarium) , cascade , eosin , combinatorial chemistry , organic chemistry , photocatalysis , medicine , staining , physics , oceanography , optoelectronics , chromatography , pathology , geology
An organic dye photoredox‐catalyzed regiospecific radical cascade annulation strategy of 2‐alkynyl‐azidoarenes to generate 3‐sulfenylindoles via vicinal thioamination of alkynes at room temperature, mediated by visible light, was developed. The method requires mild conditions, including visible light as a traceless green energy source, room temperature, eosin Y organic dye as a photoredox catalyst, ambient air as oxidant, and easily available starting materials to provide a green, efficient, metal‐ and strong‐oxidant‐free synthesis of 3‐sulfenylindoles with broad substrate scope through vicinal thioamination of alkynes.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here