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Cover Feature: Pre‐Activation‐Based Stereoselective Glycosylations (Eur. J. Org. Chem. 9/2018)
Author(s) -
Yang Bo,
Yang Weizhun,
Ramadan Sherif,
Huang Xuefei
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201800274
Subject(s) - chemistry , glycosylation , stereoselectivity , anomer , glycosyl , cover (algebra) , stereochemistry , glycosyl donor , acceptor , combinatorial chemistry , organic chemistry , catalysis , biochemistry , mechanical engineering , physics , engineering , condensed matter physics
The Cover Feature shows that pre‐activation‐based glycosylation separates donor activation and acceptor glycosylation into two distinct steps. As a result, unique stereochemical control can be achieved by judicious choices of protective groups, anomeric groups, additives, and solvents. Some highly challenging glycosyl linkages including β‐mannosides and deoxy glycosides can now be prepared with high stereoselectivities. More information can be found in the Microreview by X. Huang et al.