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Cu I ‐Mediated Degradation of Polysaccharides Leads to Fragments with Narrow Polydispersities
Author(s) -
Rahkila Jani,
Ekholm Filip S.,
Leino Reko
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201800033
Subject(s) - depolymerization , chemistry , polysaccharide , xylan , dextran , polymer science , substrate (aquarium) , starch , chemical engineering , degradation (telecommunications) , organic chemistry , telecommunications , computer science , engineering , oceanography , geology
Biomass derived oligo‐ and polysaccharides are important compounds for various applications, including biomedicine and material science. Their use, however, is often limited by inherent structural inhomogeneity of the starting materials. Here, a method for depolymerization of naturally occurring polysaccharides, including dextran, starch, xylan and galactoglucomannan, into well‐defined fragments of narrow polydispersities is described, based on the use of in situ generated Cu I species under the commonly employed CuAAC reaction conditions. The main strength of the reported method is its high versatility, both in terms of substrate scope and operational simplicity.