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Highly Efficient Copper‐Catalyzed Amidation of Benzylic Hydrocarbons Under Neutral Conditions
Author(s) -
Howard EvaLouise,
Guzzardi Norman,
Tsanova Viliyana G.,
Stika Angeliki,
Patel Bhaven
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201701759
Subject(s) - chemistry , copper , catalysis , peroxide , organic chemistry , ligand (biochemistry) , hydrocarbon , combinatorial chemistry , polymer chemistry , biochemistry , receptor
A ligand free method has been developed for the amidation of benzylic hydrocarbons. A range of benzylic amides has been prepared with the use of dicumyl peroxide and a copper catalyst in good to excellent yields.