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Base‐Promoted Sulfur‐Mediated Carbonylative Cyclization of Propargylic Amines
Author(s) -
Ying Jun,
Wang Hai,
Qi Xinxin,
Peng JinBao,
Wu XiaoFeng
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201701717
Subject(s) - chemistry , sulfur , benzene , base (topology) , medicinal chemistry , carbonylation , organic chemistry , combinatorial chemistry , catalysis , carbon monoxide , mathematical analysis , mathematics
A t BuOK‐mediated carbonylative cyclization of propargylic amines with elemental sulfur has been developed. With benzene‐1,3,5‐triyl triformate (TFBen) as a convenient CO surrogate, various substituted 1,3‐thiazolidin‐2‐ones were produced in good to excellent yields.