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Construction of 2‐Thiabicyclo[3.3.1]nonanes by Organocatalytic Asymmetric Formal [3+3] Cycloaddition
Author(s) -
Ramachary Dhevalapally B.,
Reddy P. Srinivasa,
Gujral Jagjeet
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201701617
Subject(s) - desymmetrization , cycloaddition , chemistry , organocatalysis , enantioselective synthesis , formal synthesis , stereochemistry , organic chemistry , catalysis
Powerful asymmetric desymmetrization of thiane‐3,5‐diones through formal [3+3] cycloaddition with alkyl vinyl ketones has been disclosed to access functionally rich 2‐thiabicyclo[3.3.1]nonanes in very good yields with excellent enantio‐ and diastereoselectivities by using organocatalysis.