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Recent Advances in Iodosobenzene‐Mediated Construction of Heterocyclic Scaffolds: Transition‐Metal‐Free Approaches and Scope
Author(s) -
Gayen Krishnanka Shekhar,
Chatterjee Nirbhik,
Khamarui Saikat,
Tarafdar Pradip Kumar
Publication year - 2018
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201701306
Subject(s) - hypervalent molecule , chemistry , scope (computer science) , combinatorial chemistry , environmentally friendly , frustrated lewis pair , grasp , oxidizing agent , nanotechnology , biochemical engineering , reagent , computer science , organic chemistry , lewis acids and bases , engineering , ecology , materials science , biology , programming language , catalysis
Iodosobenzene (PhIO) is a well‐known hypervalent iodine reagent for its Lewis acidic oxidizing capability. In recent times it has been repeatedly proven to be a powerful tool for the development of toxic, costly transition‐metal‐free advanced and impressive methodologies to construct diverse array of different heterocycles. In this review some selected viable and innovative strategies from 2007 to 2016 have been contemplated. Sometimes mechanistic proposals were also taken as prime consideration since synthetic organic chemists are providing fresh stimuli to reinforce the theoretical predictions to grasp the unique nature of PhIO in dissimilar conditions. Convenient and environmentally friendly cyclization and cycloaddition protocols were delineated adequately to integrate the practical findings and mechanistic points of view.