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A Highly Regioselective Palladium‐Catalyzed O,S Rearrangement of Cyclic Thiocarbonates
Author(s) -
Mahy William,
CabezasHayes Sinéad,
KociokKöhn Gabriele,
Frost Christopher G.
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201701181
Subject(s) - regioselectivity , chemistry , palladium , catalysis , intramolecular force , ligand (biochemistry) , combinatorial chemistry , organic chemistry , biochemistry , receptor
This work describes an operationally simple catalytic synthesis of cyclic S ‐thiocarbonates with predictable regioselectivity in good yields. The reaction utilizes substrates derived from ubiquitous 1,2‐diols in an atom economical intramolecular rearrangement, catalysed by an inexpensive and simple catalyst–ligand system. A crystal structure is presented that clearly confirms the regioselectivity of the reaction.