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A Direct C2‐Selective Phenoxylation and Alkoxylation of Quinoline N ‐Oxides with Various Phenols and Alcohols in the Presence of H ‐Phosphonate
Author(s) -
Bi WenZhu,
Qu Chen,
Chen XiaoLan,
Qu LingBo,
Liu ZhiDong,
Sun Kai,
Li Xu,
Zhao YuFen
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201701080
Subject(s) - phosphonate , chemistry , quinoline , phenols , alkoxy group , organic chemistry , combinatorial chemistry , medicinal chemistry , alkyl
A practical and efficient method for the synthesis of 2‐aroxy(alkoxy)quinolines has been developed by direct cross‐dehydrogenative coupling reaction between quinoline N ‐oxides and readily available phenols and alcohols in the presence of H ‐phosphonate and CCl 4 under mild conditions.
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