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Synthesis of N ‐Nitroso CHF 2 ‐Pyrazolines and Their Transformation into CHF 2 ‐Isoxazolines and ‐Pyrazoles
Author(s) -
Lebed Pavlo S.,
Fenneteau Johan,
Wu Yong,
Cossy Janine,
Mykhailiuk Pavel K.
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201700803
Subject(s) - chemistry , nitroso , nitroso compounds , medicinal chemistry , organic chemistry
N ‐Nitroso CHF 2 ‐pyrazolines were synthesized from in situ generated difluoromethyldiazomethane (CF 2 HCHN 2 ), tert ‐butyl isonitrite ( t BuONO), and alkenes. The synthesis of representative CHF 2 ‐pyrazoles and CHF 2 ‐oxazolines was also performed.
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