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Aphapolins A and B: Two Nemoralisin Diterpenoids Isolated from Aphanamixis polystachya (Wall.) R. Parker
Author(s) -
Fang FuHu,
Huang WenJun,
Zhou ShuangYan,
Han ZhengZhi,
Li ManYu,
Liu LiFang,
Wu XiaoZhen,
Yao XiaoJun,
Li Ya,
Yuan ChengShan
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201700795
Subject(s) - chemistry , stereochemistry , diterpene
Aphapolin A, a nemoralisin‐type diterpenoid possessing a unique 4/5‐fused‐ring system that is unprecedented in previously reported nemoralisin diterpenoid, and aphapolin B, a novel nemoralisin‐type diterpenoid derivative containing a benzofuran moiety, along with a new natural product were isolated from Aphanamixis polystachya (Wall.) R. Parker. Their structures and absolute configurations were elucidated by spectroscopy data, X‐ray crystallography diffraction analysis, and electronic circular dichroism calculations. Plausible biosynthetic pathways of aphapolins A and B were also delineated.