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Front Cover: Carboxamides as N ‐Alkylating Reagents of Secondary Amines in Indium‐Catalyzed Reductive Amination with a Hydrosilane (Eur. J. Org. Chem. 20/2017)
Author(s) -
Ogiwara Yohei,
Shimoda Wataru,
Ide Keisuke,
Nakajima Takumi,
Sakai Norio
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201700684
Subject(s) - chemistry , amination , reagent , catalysis , amide , amine gas treating , indium , nitrogen , reductive amination , organic chemistry , polymer chemistry , medicinal chemistry
The cover picture shows a novel molecular transformation from a carboxamide to an amine through an indium‐catalyzed reductive amination using a hydrosilane, represented by a billiards game. The two gray hydrogen balls of the hydrosilane and the blue nitrogen ball of the amine, struck by the yellow cue ball of the indium catalyst, hit the red oxygen and the blue nitrogen balls of the starting amide. The original oxygen and nitrogen balls are then replaced by the two hydrogen balls and one nitrogen ball to form the new amine structure. Details are discussed in the Communication by N. Sakai et al. on page 2866 ff (DOI: 10.1002/ejoc.201601629 ).