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AlCl 3 ‐Catalyzed Intermolecular Annulation of Thiol Derivatives and Alkynes by 1,2‐Sulfur Migration: Construction of 6‐Substituted Benzo[ b ]thiophenes
Author(s) -
Ramesh E.,
Guntreddi Tirumaleswararao,
Sahoo Akhila K.
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201700607
Subject(s) - annulation , chemistry , phthalimide , intermolecular force , thiophene , sulfur , catalysis , conjugated system , medicinal chemistry , oxidative phosphorylation , cleavage (geology) , stereochemistry , organic chemistry , photochemistry , combinatorial chemistry , polymer , molecule , geotechnical engineering , fracture (geology) , engineering , biochemistry
A method for the AlCl 3 ‐catalyzed intermolecular oxidative annulation of N ‐(arylthio)phthalimide derivatives with alkynes has been developed. The annulation reaction occurs at room temperature and involves the oxidative cleavage of the S–N bond and 1,2‐sulfur migration, which leads to the construction of diverse arrays of π‐conjugated 6‐substituted 2,3‐diarylbenzo[ b ]thiophene derivatives.