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Ruthenium‐Catalyzed, Keto‐Directed, Site‐Selective C–H Activation of Diverse Chromanones with Alkenes
Author(s) -
Bakthadoss Manickam,
Kumar Polu Vijay,
Reddy Tatiparthi Sushmitha
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201700513
Subject(s) - chemistry , ruthenium , catalysis , stereoselectivity , chelation , combinatorial chemistry , oxidative coupling of methane , stereochemistry , organic chemistry
A simple and versatile approach towards the synthesis of highly functionalized C5‐alkenylated chromanones in good yields in a regio‐ and stereoselective fashion was explored. This reaction takes place through chelation‐aided oxidative coupling of keto‐directed, site‐selective C–H activation by using chromanones with alkenes in the presence of a ruthenium catalyst under mild conditions.