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ABNO‐Catalyzed Aerobic Oxidative Synthesis of 2‐Substituted 4 H ‐3,1‐Benzoxazines and Quinazolines
Author(s) -
Ma Jiaqi,
Wan Yan,
Hong Chao,
Li Meichao,
Hu Xinquan,
Mo Weimin,
Hu Baoxiang,
Sun Nan,
Jin Liqun,
Shen Zhenlu
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201700384
Subject(s) - chemistry , yield (engineering) , catalysis , oxidative phosphorylation , reaction conditions , organic chemistry , cascade reaction , combinatorial chemistry , transition metal , medicinal chemistry , biochemistry , materials science , metallurgy
A new transition‐metal‐free 9‐azabicyclo[3.3.1]nonan‐ N ‐oxyl (ABNO) catalyzed aerobic oxidative synthesis of 2‐substituted 4 H ‐3,1‐benzoxazines and quinazolines has been developed through cascade reaction of aldehydes with 2‐aminobenzyl alcohols and 2‐aminobenzylamines, respectively. Under the optimal reaction conditions, the two kinds of heterocycles were obtained in 72–97 % isolated yield.