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[3+2] Cycloaddition between 3‐Isothiocyanato Oxindoles and Nitroso Compounds
Author(s) -
Zhao HongWu,
Chen XiaoQin,
Zhao YuDi,
Liu YueYang,
Pang HaiLiang,
Song XiuQing,
Tian Ting,
Li Bo,
Yang Zhao,
Du Juan,
Feng NingNing
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201700367
Subject(s) - cycloaddition , chemistry , nitroso , nitroso compounds , yield (engineering) , medicinal chemistry , stereochemistry , organic chemistry , catalysis , materials science , metallurgy
Catalyzed by 10 mol‐% PhCO 2 H, the [3+2] cycloaddition between 3‐isothiocyanato oxindoles and nitroso compounds proceeded readily to deliver 1,2,4‐oxadiazolidine‐3‐thione‐fused spirooxindoles in 40–82 % yield. The structures of the title compounds were firmly confirmed by X‐ray single‐crystal structure analysis.