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Front Cover: Methylsulfenylation of Electrophilic Carbon Atoms: Reaction Development, Scope, and Mechanism (Eur. J. Org. Chem. 12/2017)
Author(s) -
Pereira Adriane A.,
Pereira Amanda S.,
de Mello Amanda C.,
Carpanez Arthur G.,
Horta Bruno A. C.,
Amarante Giovanni W.
Publication year - 2017
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201700354
Subject(s) - chemistry , electrophile , deoxygenation , adduct , nucleophile , chalcone , front cover , combinatorial chemistry , photochemistry , medicinal chemistry , organic chemistry , cover (algebra) , catalysis , mechanical engineering , engineering
The cover picture shows a chemoselective C–S bond formation through a metal‐free process under microwave irradiation. The methylsulfenylation of electrophilic carbons is possible by using cheap and commercially available dimethylsulfoxide. Under the optimized reaction conditions, chalcone, dibenzylideneacetone, as well as Morita–Baylis–Hillman adduct derivatives were successfully sulfenylated. Deoxygenation of DMSO and nucleophilic addition of a sulphur intermediate are the key steps for this process. Details are discussed in the Communication by B. A. C. Horta, G. W. Amarante et al. on page 1578 ff (DOI: 10.1002/ejoc.201601613 ).